Solid Dosage Forms-Hicand

Composition
- Hicand 8: Each tablet contains 8 mg of candesartan cilexetil.
- Hicand 16: Each tablet contains 16 mg of candesartan cilexetil.
Properties
Hicand contains candesartan cilexetil which belongs to angiotensin II receptor antagonists. It makes the blood vessels relax and widen this helps to lower the blood pressure and makes it easier for the heart to pump blood to all parts of the body.
Indications
- Hypertension.
- Heart failure.
Dosage
Hypertension:
- Adults:
The recommended initial dose is 8 mg once daily. 
This dose can be increased to 16 mg once daily and to a maximum of 32 mg once daily.
- Patients with renal and mild hepatic impairment: 
The starting dose is 4 mg once daily. 
- Children ( 6 - 18 ) years:
• For patients weighing < 50 kg: 
 The recommended starting dose is 4 mg once daily this dose can 
be increased to 8 mg once daily.
• For patients weighing ≥ 50 kg: 
 The recommended starting dose is 4 mg once daily this dose can 
be increased to 8 mg or 16 mg once daily.
Heart failure:
The recommended starting dose is 4 mg once daily.
This dose can be increased to a maximum 32 mg once daily. 
Contraindications
- Hypersensitivity to candesartan cilexetil.
- Second and third trimesters of pregnancy.
- Severe hepatic impairment.
- Children below 1 year.
Side effects
These side effects may be occur such as:
- Respiratory tract infections.
- Headache and dizziness.
- Hypotension.
- Changes in blood test results such as ( hyperkalaemia and 
increased serum creatinine).
Precautions
Tell your doctor in these cases:
- Breast-feeding and first trimester of pregnancy.
- Haemodialysis patients.
- Anaesthesia and surgery.
- Hypotension symptoms
Drug interactions
Tell your doctor if you take other medicines such as:
- Aliskiren. 
- Non steroidal anti-inflammatory drugs (NSAIDs).
- Potassium supplements or salt substitutes.
Package
Each box contains: 3 × 10 Tablets.
Storage
Store at a temperature below 30 ºC.